초록접수 현황
| 20F-168 | 구연 발표 |
The assessment of pulmonary function to predict postoperative cardiopulmonary complications after esophageal cancer surgery
Tae Ho Kim, MD 1; Hyun Lee MD, PhD2; Sumin Shin, MD1; Jong Ho Cho, MD, PhD1; Yong Soo Choi, MD, PhD1; Jhingook Kim, MD1; Jae Ill Zo, MD, PhD1; Young Mog Shim, MD, PhD1; Hye Yoon Park, MD, PhD3; Hong Kwan Kim, MD, PhD1
1 Department of Thoracic and Cardiovascular Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea
2 Department of Medicine, Hanyang Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea
3 Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea
Purpose : The role of pulmonary function test to predict postoperative pulmonary complications(PPC) in patients with esophageal cancer who undergo esophagectomy has not been well elucidated.
Methods : From January 2013 to December 2017, a retrospective cohort study of 810 patients with esophageal cancer was performed to evaluate the role of forced expiratory volume in 1 second (FEV1) and diffusing capacity of the lung for carbon monoxide (DLco) to predict pulmonary complications after esophagectomy. Patients were classified into low and high lung function groups by the cutoff of the lowest fifth quintile of lung function.
Results : The adjusted RRs for the occurrence of PPC in the low FEV1 group relative to the high FEV1 group was 1.48 (95% CI,1.09-2.00) and 1.98 (95% CI,1.46-2.68) in the low DLco group relative to the high DLco group. The adjusted RR for PPC was highest in the low FEV1/low DLco group (2.30 [95% CI,1.53-3.44]), followed by the high FEV1/low DLco group (2.06 [95% CI,1.42-2.99]) compared to the high FEV1/high DLco group. However, the adjusted RR for PPC in the low FEV1/high DLco group relative to the high FEV1/high DLco group was not significantly increased. Neither FEV1%pred nor DLco%pred had prognostic value to predict postoperative cardiac complications in patients with esophageal cancer.
Conclusion : Patients with esophageal cancer with decreased lung function have a higher risk of developing PPC. Our study suggests that the pulmonary function test are useful to predict PPC in patients with esophageal cancer, respectively.
Methods : From January 2013 to December 2017, a retrospective cohort study of 810 patients with esophageal cancer was performed to evaluate the role of forced expiratory volume in 1 second (FEV1) and diffusing capacity of the lung for carbon monoxide (DLco) to predict pulmonary complications after esophagectomy. Patients were classified into low and high lung function groups by the cutoff of the lowest fifth quintile of lung function.
Results : The adjusted RRs for the occurrence of PPC in the low FEV1 group relative to the high FEV1 group was 1.48 (95% CI,1.09-2.00) and 1.98 (95% CI,1.46-2.68) in the low DLco group relative to the high DLco group. The adjusted RR for PPC was highest in the low FEV1/low DLco group (2.30 [95% CI,1.53-3.44]), followed by the high FEV1/low DLco group (2.06 [95% CI,1.42-2.99]) compared to the high FEV1/high DLco group. However, the adjusted RR for PPC in the low FEV1/high DLco group relative to the high FEV1/high DLco group was not significantly increased. Neither FEV1%pred nor DLco%pred had prognostic value to predict postoperative cardiac complications in patients with esophageal cancer.
Conclusion : Patients with esophageal cancer with decreased lung function have a higher risk of developing PPC. Our study suggests that the pulmonary function test are useful to predict PPC in patients with esophageal cancer, respectively.
첨부파일 : 초록 tables.docx
책임저자: Hong Kwan Kim
Department of Thoracic and Cardiovascular Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea
발표자: Tae Ho Kim, E-mail : roohoguy@gmail.com