초록접수 현황
| 20F-111 | 구연 발표 |
Favorable outcomes of rheolytic thrombectomy for the treatment of deep venous thrombosis in lower limb
Myeong su Kim¹, Tae-Hoon Kim¹, Ha Lee¹, Seung jun Song², Wan Kee Kim², Suk-Won Song¹, Kyung-Jong Yoo³
¹Department of Thoracic and Cardiovascular Surgery, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea
²Department of Thoracic and Cardiovascular Surgery, Yongin Severance Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea
³Department of Thoracic and Cardiovascular Surgery, Cardiovascular Hospital, Severance Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea
Purpose : The aim of this study is to evaluate the efficacy and safety of rheolytic thrombectomy (RT) for the treatment of deep venous thrombosis (DVT) in lower limb.
Methods : A retrospective study was performed on 157 patients with DVT in lower limb from 2008 to 2019. Twenty-four patients treated with RT, and the others treated with catheter directed thrombolysis with or without mechanical thrombectomy. Through computed tomography scan, these two groups were compared.
Results : Mean age was 58.2 ± 16.5 year-old and there were 71 male. Mean follow up period was 16.7 ± 26.7 month. According to postoperative thrombus removal grade, significantly less patients showed grade I (<50% reduction; 12.5% vs. 33%, p=0.43) and more patients were grade III (100% reduction; 41.6% vs. 24%, p=0.89) in RT group. The average urokinase administration dose (208000 ± 86000 IU vs. 825000 ± 927000 IU, p<0.001) and duration of thrombolysis (0.5 hour vs. 12.6 ± 16.3 hour, p<0.001) were significantly smaller and shorter in RT group. More patients in RT group experienced postoperative hemolysis (45.8% vs. 9.0%, p<0.001). Duration of venous active drug use was significantly shorter in RT group (3.8 ± 4.5 month vs. 19.0 ± 28.3 month, p<0.001). There were no differences in re-intervention rate and no life-threatening complications in both groups.
Conclusion : This study indicated the use of RT in the treatment of DVT in lower limb is safe and feasible and showed favorable outcomes, especially in reduction of thrombus burden and also, relief of functional symptom. However, postoperative hemolysis should be carefully monitored.
Methods : A retrospective study was performed on 157 patients with DVT in lower limb from 2008 to 2019. Twenty-four patients treated with RT, and the others treated with catheter directed thrombolysis with or without mechanical thrombectomy. Through computed tomography scan, these two groups were compared.
Results : Mean age was 58.2 ± 16.5 year-old and there were 71 male. Mean follow up period was 16.7 ± 26.7 month. According to postoperative thrombus removal grade, significantly less patients showed grade I (<50% reduction; 12.5% vs. 33%, p=0.43) and more patients were grade III (100% reduction; 41.6% vs. 24%, p=0.89) in RT group. The average urokinase administration dose (208000 ± 86000 IU vs. 825000 ± 927000 IU, p<0.001) and duration of thrombolysis (0.5 hour vs. 12.6 ± 16.3 hour, p<0.001) were significantly smaller and shorter in RT group. More patients in RT group experienced postoperative hemolysis (45.8% vs. 9.0%, p<0.001). Duration of venous active drug use was significantly shorter in RT group (3.8 ± 4.5 month vs. 19.0 ± 28.3 month, p<0.001). There were no differences in re-intervention rate and no life-threatening complications in both groups.
Conclusion : This study indicated the use of RT in the treatment of DVT in lower limb is safe and feasible and showed favorable outcomes, especially in reduction of thrombus burden and also, relief of functional symptom. However, postoperative hemolysis should be carefully monitored.
첨부파일 : Table.docx
책임저자: Suk-Won Song
Department of Thoracic and Cardiovascular Surgery, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea
발표자: Myeong su Kim, E-mail : mmotion11@gmail.com