Contemporay outcome after pulmonary artery banding in complete atrioventricular septal defect: how the band tightness affect the outcome?
Mi Jin Kim1, Seulgi Cha1, Jae Suk Baek1, Jeong Jin Yu1, Young-Hwue Kim1, Eun suk Choi2., Bo Sang Kwon2, Tae-Jin Yun2, Chun Soo Park2
1 Division of Pediatric Cardiology, and 2 Division of Cardiac Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea
Purpose : Pulmonary artery banding (PAB) remains a surgical option for patients with complete atrioventricular septal defect (AVSD) presenting earlier. This study investigated the outcomes after PAB in patients with complete AVSD.
Methods : From 2000 through 2019, a total of 34 infants (median age, 2.09months) who underwent PAB for complete AVSD were included in this study. Preoperative and operative characteristics were analyzed as independent variables for identifying factors associated with adverse outcome, which was defined as prolonged stay in the intensive care unit (>10 days) or in-hospital death, using multiple logistic regression model. ROC analysis indicated 4.7mm in diameter measured by echocardiography during immediate postoperative period as a threshold band tightness for adverse outcome (AUC 0.854, 95% CI 0.705~1.000).
Results : The median age and weight were 43 days (IQR, 22~64 days) and 3.6 kg (IQR, 2.7~4.1kg), respectively. There were 4 in-hospital deaths. Median ICU stay and hospital stay were 8 days (6~14 days), and 14 days (9~22 days), respectively. In multivariable analysis, preoperative use of intravenous inotropes (OR 5.33, CI 1.16~24.47; p=0.031), ventilator care (OR 10, CI 1.59~63.1; p=0.014) and Loose band (<4.7mm) (OR 63.0, CI 5.75~690.37; p=0.001) were identified as significant factors associated with adverse outcome (Table). The level of B-natriuretic peptide similarly decreased after PAB regardless of band tightness, although the probability of worsening in atrioventricular valve regurgitation was decreasing in patients with tighter band (Figure).
Conclusion : PAB is a viable option for patients with early presenting complete AVSD. Tighter band might be better in terms of immediate postoperative outcomes and AVV regurgitation.
책임저자: Chun Soo Park
Division of Cardiac Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea
발표자: Mijin Kim, E-mail : atlranta83@hanmail.net