초록접수 현황
| 20F-113 | 구연 발표 |
Association between sarcopenia and physical function among preoperative lung cancer patients
Sumin Shin1, Sunga Kong2.3, Jae Kyung Lee2, Genehee Lee2,3, Danbee Kang3, Juhee Cho3,4,5, Jong Ho Cho1, Hong Kwan Kim1, Yong Soo Choi1, Jhingook Kim1, Jae Ill Zo1, Young Mog Shim1, Hye Yun Park6 and Dong Wook Shin7
1 Department of Thoracic and Cardiovascular Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea
2 Patient-Centered Outcomes Research Institute, Samsung Medical Center, Seoul, Korea
3 Department of Clinical Research Design and Evaluation, SAIHST, Sungkyunkwan University, Seoul, Korea
4 Center for Clinical Epidemiology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea
5 Department of Epidemiology and Medicine, and Welch Center for Prevention, Epidemiology, and Clinical Research, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA
6 Division of Pulmonary and Critical Care Medicine, Department of Medicine, Samsung Medical Center, Sungkyunkwan University, School of Medicine, Seoul, Korea
7 Department of Family Medicine & Supportive Care Center, Samsung Medical Center, Seoul,Korea
Purpose : We aimed to investigate the prevalence of sarcopenia using new diagnostic criteria and association of sarcopenia with cardiopulmonary function and physical activity (PA) in preoperative lung cancer patients.
Methods : The data of 614 patients were obtained from the CATCH-LUNG cohort study. Patients were classified into three groups—normal (n=520), pre-sarcopenia (n=60, low skeletal muscle mass index only), and sarcopenia (n=34, low SMI and strength). Cardiopulmonary function was measured using the 6-min walk test (6MWT), and PA was objectively measured using a wearable device.
Results : The adjusted odds ratio (aOR) for a <400-m distance in 6MWT was 3.52 (95% confidence interval [CI] 1.34-9.21) and 6.63 (95% CI 2.25-19.60) in the pre-sarcopenia and sarcopenia groups, respectively, compared to that in the normal group. The aOR (95% CI) for <5000 steps/day was 1.64 (0.65-4.16) and 4.20 (1.55-11.38) in the pre-sarcopenia and sarcopenia groups, respectively, compared to that in the normal group.
Conclusion : In conclusion, the prevalence of pre-sarcopenia and sarcopenia was 9.8% and 5.5%, respectively, among preoperative lung cancer patients. Cardiopulmonary function and physical activity were significantly lower in the pre-sarcopenia and sarcopenia groups than in the normal group. Patients with sarcopenia had more robust findings, suggesting the importance of muscle strength and mass.
Methods : The data of 614 patients were obtained from the CATCH-LUNG cohort study. Patients were classified into three groups—normal (n=520), pre-sarcopenia (n=60, low skeletal muscle mass index only), and sarcopenia (n=34, low SMI and strength). Cardiopulmonary function was measured using the 6-min walk test (6MWT), and PA was objectively measured using a wearable device.
Results : The adjusted odds ratio (aOR) for a <400-m distance in 6MWT was 3.52 (95% confidence interval [CI] 1.34-9.21) and 6.63 (95% CI 2.25-19.60) in the pre-sarcopenia and sarcopenia groups, respectively, compared to that in the normal group. The aOR (95% CI) for <5000 steps/day was 1.64 (0.65-4.16) and 4.20 (1.55-11.38) in the pre-sarcopenia and sarcopenia groups, respectively, compared to that in the normal group.
Conclusion : In conclusion, the prevalence of pre-sarcopenia and sarcopenia was 9.8% and 5.5%, respectively, among preoperative lung cancer patients. Cardiopulmonary function and physical activity were significantly lower in the pre-sarcopenia and sarcopenia groups than in the normal group. Patients with sarcopenia had more robust findings, suggesting the importance of muscle strength and mass.
책임저자: Sumin Shin
Department of Thoracic and Cardiovascular Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea
발표자: Sumin Shin, E-mail : essennee@gmail.com