초록접수 현황
| 20F-096 | 구연 발표 |
Large tumor size in video-assisted thoracoscopic lobectomy for non-small cell lung cancer: does it still matter?
Jeonghee Yun, Junghee Lee, Sumin Shin, Hong Kwan Kim, Yong Soo Choi, Jhingook Kim, Jae Il Zo,Young Mog Shim, Jong Ho Cho
Department of Thoracic and Cardiovascular Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, 81 Irwon-ro, Gangnam-gu, Seoul 06531, Republic of Korea
Purpose : Large lung tumors have been regarded as a contraindication for video-assisted thoracoscopic surgery (VATS) because of the increased risk of tumor cell spillage. This study aimed to compare perioperative outcomes and oncological validity between VATS lobectomy and open lobectomy for non-small cell lung cancer (NSCLC) larger than 5 cm.
Methods : We retrospectively reviewed 355 lobectomy patients with clinical N0 NSCLC larger than 5 cm between January 2009 and December 2016. Patients who required chest wall resection or sleeve resection were excluded. The patients were divided into a VATS group (n = 132) and a thoracotomy group (n = 223). Propensity score matching (1:1) was applied.
Results : After propensity score matching, 204 patients were matched and clinical characteristics of the two groups were well balanced. The VATS group was associated with a shorter length of hospital stay (6 days [range, 5–8] vs 7 days [range, 6–10]; p < 0.001). There was no difference in cumulative incidence of ipsilateral pleural recurrence (p = 0.582). The 5-year OS rate and RFS were 71.5%, 60.1% in the VATS group and 64.4%, 51.5% in the thoracotomy group. There were no significant differences in the OS and RFS between the VATS and thoracotomy groups (OS, p = 0.390; RFS, p = 0.210).
Conclusion : In clinical N0 NSCLC larger than 5 cm, VATS lobectomy resulted in shorter hospital stay and similar survival outcome compared with open lobectomy. Based on these results, VATS lobectomy is a valuable option in this subset of patients.
Methods : We retrospectively reviewed 355 lobectomy patients with clinical N0 NSCLC larger than 5 cm between January 2009 and December 2016. Patients who required chest wall resection or sleeve resection were excluded. The patients were divided into a VATS group (n = 132) and a thoracotomy group (n = 223). Propensity score matching (1:1) was applied.
Results : After propensity score matching, 204 patients were matched and clinical characteristics of the two groups were well balanced. The VATS group was associated with a shorter length of hospital stay (6 days [range, 5–8] vs 7 days [range, 6–10]; p < 0.001). There was no difference in cumulative incidence of ipsilateral pleural recurrence (p = 0.582). The 5-year OS rate and RFS were 71.5%, 60.1% in the VATS group and 64.4%, 51.5% in the thoracotomy group. There were no significant differences in the OS and RFS between the VATS and thoracotomy groups (OS, p = 0.390; RFS, p = 0.210).
Conclusion : In clinical N0 NSCLC larger than 5 cm, VATS lobectomy resulted in shorter hospital stay and similar survival outcome compared with open lobectomy. Based on these results, VATS lobectomy is a valuable option in this subset of patients.
책임저자: Jong Ho Cho
Department of Thoracic and Cardiovascular Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, 81 Irwon-ro, Gangnam-gu, Seoul 06531, Republic of Korea
발표자: Jeonghee Yun, E-mail : yjhms08@gmail.com