초록접수 현황
| 20F-029 | 구연 발표 |
Radiologic and clinical features of screening-detected pulmonary invasive mucinous adenocarcinoma
Dae Hyeon Kim, So Young Bae, Kwon Joong Na, Samina Park, Hyun Joo Lee, Chang Hyun Kang, Young Tae Kim, In Kyu Park
Department of Thoracic and Cardiovascular Surgery, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Republic of Korea
Purpose : The distinctive features of invasive mucinous adenocarcinoma (IMA) from non-mucinous adenocarcinoma had been suggested largely based on studies with advanced stage IMA and the data about early stage IMA are sparse. We evaluated the radiologic and clinical characteristics and the prognosis of screening-detected early stage IMA (SD-IMA).
Methods : Total of 93 patients who underwent curative surgery for SD-IMAs (≤3cm) from 2013 to 2019 were reviewed retrospectively. Data about radiologic characteristics, clinic-pathologic findings, and prognosis of were obtained. The disease-free survival (DFS) was the primary endpoint for prognosis. The sensitivity of pretreatment histologic diagnosis and prognosis of SD-IMA were evaluated.
Results : The dominant locations of SD-IMAs were both lower lobes (73.2%) and one-quarter of tumors were located in other than lower lobes. Eighty-seven (93.5%) nodules were located in the periphery one-third of the lung and very close from visceral pleura (mean distance = 2.4±5.0mm). The SD-IMAs were dominantly solid and high consolidation pattern nodule in CT findings (part-solid nodule - 39.8% and solid nodule - 55.7%). The sensitivity of preoperative tissue diagnosis was 61.1%. Pathologic stages of SD-IMAs were pIA in 77.4%, pIB in 16.1%). Recurrences occurred in 6 patients and no death occurred during follow-up period. The 3 and 5-year DFS rates were 93.1 % and 88.2%.
Conclusion : SD-IMA was mostly presented as part-solid or solid nodule at peripheral portion of lung. The accuracy of histologic diagnosis of SD-IMA with small tissue samples or frozen examination was not high. SD-IMA showed favorable prognosis after surgical treatment including sublobar resection based on radiologic features.
Methods : Total of 93 patients who underwent curative surgery for SD-IMAs (≤3cm) from 2013 to 2019 were reviewed retrospectively. Data about radiologic characteristics, clinic-pathologic findings, and prognosis of were obtained. The disease-free survival (DFS) was the primary endpoint for prognosis. The sensitivity of pretreatment histologic diagnosis and prognosis of SD-IMA were evaluated.
Results : The dominant locations of SD-IMAs were both lower lobes (73.2%) and one-quarter of tumors were located in other than lower lobes. Eighty-seven (93.5%) nodules were located in the periphery one-third of the lung and very close from visceral pleura (mean distance = 2.4±5.0mm). The SD-IMAs were dominantly solid and high consolidation pattern nodule in CT findings (part-solid nodule - 39.8% and solid nodule - 55.7%). The sensitivity of preoperative tissue diagnosis was 61.1%. Pathologic stages of SD-IMAs were pIA in 77.4%, pIB in 16.1%). Recurrences occurred in 6 patients and no death occurred during follow-up period. The 3 and 5-year DFS rates were 93.1 % and 88.2%.
Conclusion : SD-IMA was mostly presented as part-solid or solid nodule at peripheral portion of lung. The accuracy of histologic diagnosis of SD-IMA with small tissue samples or frozen examination was not high. SD-IMA showed favorable prognosis after surgical treatment including sublobar resection based on radiologic features.
책임저자: In Kyu Park
Department of Thoracic and Cardiovascular Surgery, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Republic of Korea
발표자: Dae Hyeon Kim, E-mail : eogus8051@gmail.com