Case Report: Successful Management of ASD with PAH
Younggi Jung, Jae Seung Shin, Hong Ju Shin
Department of Thoracic and Cardiovascular Surgery, Korea University Ansan Hospital, Korea University College of Medicine, Seoul, Republic of Korea
Purpose : Here we present the case of a patient with pulmonary arterial hypertension (PAH) and large atrial septal defect (ASD) who presented with NYHA Class III symptoms. Initial parameters revealed the patient was at high risk for operation (mPAP 53mmHg, PVR 9.43 WU) thus pre-operative medical therapy was conducted for several months and thereafter surgical repair of ASD performed which lead to dramatic improvement of PAH.
Methods : Patient was initiated with Endothelin receptor antagonist (ERA) and PDE5 inhibitor and routine check up at outpatient department was done prior to surgical repairment. All parameters partially improved after 6 months of medical therapy thus surgical repair of ASD was performed on January, 2019.
Results : Recent follow up revealed much improvement in all parameters. Functional classification was improved from class III to class II. Right heart catheterization(RHC) showed that PVR has decreased from 9.43 WU to 3.7 WU with mPAP of 30mmHg
Conclusion : High risk PAH patient can be successfully treated by combination of pre-operative medical therapy and surgical repairment of underlying congenital deformity.
책임저자: Hong Ju Shin
Department of Thoracic and Cardiovascular Surgery, Korea University Ansan Hospital, Korea University College of Medicine, Seoul, Republic of Korea
발표자: Younggi Jung, E-mail : schifer@naver.com