초록접수 현황
| 19F-031 | 포럼 발표 |
Outcomes in Influenza A Viral Pneumonia-Related Acute Respiratory Failure Patients with Extracorporeal Membrane Oxygenation Support
Bong Suk Park, Hyoung Soo Kim
Department of Thoracic and Cardiovascular Surgery, Sacred Heart Hospital, Hanllym University College of Medicine, Gyeonggi-do, Republic of Korea
Purpose : Influenza A can cause acute respiratory distress syndrome (ARDS) and lead to severe impairment in gas exchange. This study was designed to describe our center experience about influenza A viral pneumonia-related ARDS with extracorporeal membrane oxygenation (ECMO)
Methods : Data including patient characteristics, laboratory results, and hospital course for patients with ECMO due to influenza A-related ARDS were retrospectively obtained from our institutional database between February 2016 and January 2019
Results : Total seven patients were enrolled in this study, one of whom died, three of whom underwent bilateral lung transplantation, and three of whom survived. The mean age of patients was 45±14.1 years old and 3 patients were female. Before ECMO treatment, the mean Simplified Acute Physiology Score Ⅱ and Sequential Organ Failure Assessment score were 41±7.6 and 10±1.3, respectively. The mean time interval between the mechanical ventilation and the ECMO were 17±21.6 hours and mean PaO2/FiO2 before ECMO were 57±11.6. In daily sputum and blood cultures, mean period of identification after ECMO starting were 7±3.1 days and 15±13.1 days, respectively, and most common pathogen was carbapenem resistant Acinectobacter baumannii (80%) in sputum and methicillin resistant staphylococcus epidermidis (60%) in blood. Without one patient dead from sudden ECMO circuit shutdown, 30-day survival rate was 85.7%. Although small numbers of patients make it hard to prove statistically, procalcitonin and C-reative protein levels tended to differ between the survival and death or transplantation groups.
Conclusion : In influenza A-related ARDS, VV ECMO could be a good treatment option and lung transplantation also might be considered.
Methods : Data including patient characteristics, laboratory results, and hospital course for patients with ECMO due to influenza A-related ARDS were retrospectively obtained from our institutional database between February 2016 and January 2019
Results : Total seven patients were enrolled in this study, one of whom died, three of whom underwent bilateral lung transplantation, and three of whom survived. The mean age of patients was 45±14.1 years old and 3 patients were female. Before ECMO treatment, the mean Simplified Acute Physiology Score Ⅱ and Sequential Organ Failure Assessment score were 41±7.6 and 10±1.3, respectively. The mean time interval between the mechanical ventilation and the ECMO were 17±21.6 hours and mean PaO2/FiO2 before ECMO were 57±11.6. In daily sputum and blood cultures, mean period of identification after ECMO starting were 7±3.1 days and 15±13.1 days, respectively, and most common pathogen was carbapenem resistant Acinectobacter baumannii (80%) in sputum and methicillin resistant staphylococcus epidermidis (60%) in blood. Without one patient dead from sudden ECMO circuit shutdown, 30-day survival rate was 85.7%. Although small numbers of patients make it hard to prove statistically, procalcitonin and C-reative protein levels tended to differ between the survival and death or transplantation groups.
Conclusion : In influenza A-related ARDS, VV ECMO could be a good treatment option and lung transplantation also might be considered.
책임저자: Hyoung Soo Kim
Department of Thoracic and Cardiovascular Surgery, Sacred Heart Hospital, Hanllym University College of Medicine, Gyeonggi-do, Republic of Korea
발표자: Bong Suk Park, E-mail : pbsthr@hallym.or.kr