초록접수 현황
| 16F-278 | 구연 발표 |
Does the Method of Mediastinal Staging Cause the Mediastinal Nodal Clearance Following Trimodality Therapy?
Jong Ho Cho¹, Hong-Kwan Kim¹, Yong Soo Choi¹, Jae Ill Zo¹, Young Mog Shim¹, Kwhanmien Kim², Jhingook Kim¹
¹Department of Thoracic and Cardiovascular Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea, ²Department of Thoracic Cardiovascular Surgery, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Gyeonggi-do, Korea
Background : The aim of our study was to investigate whether the method of mediastinal staging could influence the mediastinal nodal clearance following trimodality therapy.
Methods : We retrospectively reviewed medical records of 574 patients with clinical stage IIIA-N2 non-small cell lung cancer who underwent surgery after neoadjuvant CCRT from 1997 to 2013. Clinical outcomes were analyzed and compared in those who had EBUS (n = 147), Mediastinoscopy (n =341), and others (n=86) after neoadjuvant CCRT in a single institution.
Results : The median number of dissected lymph node during the pulmonary resection was 20 (range, 0-50) in EBUS, 14 (range, 1-52) in mediastinoscopy, and 18 (range, 4-40) in others (p<0.001). The median number of lymph node metastases was 2 (range, 0-23) in EBUS, 1 (range, 0-26) in mediastinoscopy, and 0 (range,0-14) in others (p<0.001). There were no differences of age,gender, cell type, surgical extent, bulk N2 between these groups.
The mediastinal nodal clearance rate (ypN0 or 1) after surgery was 36 % (54/147) in EBUS, 58% (198/341) in mediastinoscopy, and 60.5% (52/86) in others (p<0.001). The ypN0 rate was 28.6% (42/147) in EBUS, 41.9% (143/341) in mediastinoscopy, and 51.2% (44/86) in others (p=0.001).
Conclusion : We found that the mediastinal nodal clearance rate (ypN0/1) after surgery was higher in mediastinoscopy than in EBUS. The method of mediastinal staging could influence ypN stage following trimodality therapy.
Methods : We retrospectively reviewed medical records of 574 patients with clinical stage IIIA-N2 non-small cell lung cancer who underwent surgery after neoadjuvant CCRT from 1997 to 2013. Clinical outcomes were analyzed and compared in those who had EBUS (n = 147), Mediastinoscopy (n =341), and others (n=86) after neoadjuvant CCRT in a single institution.
Results : The median number of dissected lymph node during the pulmonary resection was 20 (range, 0-50) in EBUS, 14 (range, 1-52) in mediastinoscopy, and 18 (range, 4-40) in others (p<0.001). The median number of lymph node metastases was 2 (range, 0-23) in EBUS, 1 (range, 0-26) in mediastinoscopy, and 0 (range,0-14) in others (p<0.001). There were no differences of age,gender, cell type, surgical extent, bulk N2 between these groups.
The mediastinal nodal clearance rate (ypN0 or 1) after surgery was 36 % (54/147) in EBUS, 58% (198/341) in mediastinoscopy, and 60.5% (52/86) in others (p<0.001). The ypN0 rate was 28.6% (42/147) in EBUS, 41.9% (143/341) in mediastinoscopy, and 51.2% (44/86) in others (p=0.001).
Conclusion : We found that the mediastinal nodal clearance rate (ypN0/1) after surgery was higher in mediastinoscopy than in EBUS. The method of mediastinal staging could influence ypN stage following trimodality therapy.
책임저자: Jhingook Kim
Department of Thoracic and Cardiovascular Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea
발표자: Jong Ho Cho, E-mail : jongho.cho@gmail.com