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16F-151 포럼 발표

Pleural Adhesion does Not Influence Recurrence and Survival after Lobectomy for T1-2N0 Lung Cancer
SeHa Ahn, YongJin Chang, DeogGon Cho, KyuDo Cho, ChulUng Kang, MinSub Jo
Department of Thoracic and Cardiovascular Surgery, St. Vincent`s Hospital, The Catholic University College of Medicine, Gyeonggi-do, Korea

Background : The various factors are related to the prognosis of complete resection of non-small cell lung cancer. The relationship between pleural adhesion, and the recurrence rate and overall survival after lobectomy for non-small cell lung cancer is unclear. The aim of this study is to figure out survival and recurrence rate of T1-2N0 lung cancer patients with pleural adhesion after lobectomy.

Methods : The retrospective analysis was initiated to 142 patients diagnosed as clinical T1-2N0 after video-assisted thoracoscopic surgery (VATS) or thoracotomic lobectomy for treatment of non-small cell lung cancer from Jan. 2006 to Aug. 2011. To find out the impact of pleural adhesion, the patients with N stage and T3 were excluded. The definition of pleural adhesion includes from diffuse adhesion to the adhesion on the lobe where tumor is located. The patients were divided in two groups: adhesion (group A, 40 patients) and non-adhesion (group N-A, 102 patients). The chest wall dissection including intercostal muscle was done in clinical T2 patients if pleural adhesion existed on the lobe that tumor is located.

Results : The histologic types of lung cancer were followed: adenocarcinoma in 81 patients, squamous cell in 47 and other types in 14. The median follow-up was 66.5 months (range, 1 to 122 months). The overall 5-year survival was 90.3%. Disease-free 5-year survival was 80.1%. There was no statistical difference in Disease-free-5-year survival (p=0.6) and no difference in overall survival (p=0.691) when the two groups were compared.

Conclusion : Pleural adhesion did not affect the prognosis of patients, who had lobectomy for clinical T1-2N0 non-small lung cancer.


책임저자: DeogGon Cho
Department of Thoracic and Cardiovascular Surgery, St. Vincent`s Hospital, The Catholic University College of Medicine, Gyeonggi-do, Korea
발표자: SeHa Ahn, E-mail : seha1228@daum.net

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