초록접수 현황
| 16F-095 | 구연 발표 |
Heart Transplantation Bridged by Extracorporeal Life Support in the Adults: Experience from Samsung Medical Center
Jun Ho Lee, Yang Hyun Cho, Dong Seop Jeong, Ji-Hyuk Yang, Kiick Sung, Wook Sung Kim, Tae-Gook Jun, Young Tak Lee, Pyo Won Park
Department of Thoracic and Cardiovascular Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea
Background : Although extracorporeal life support (ECLS) is not used as a bridge to heart transplantation in most of Western countries, it is the only treatment for heart failure patients who are suffering from cardiogenic shock. However, there is only few report on the outcomes of heart transplantation bridged by ECLS.
Methods : We reviewed patients who had heart transplantation between December 2003 and July 2016. We excluded patients under 18 years-old. We defined heart transplantations which was performed while the patients were under ECLS as ECLS group (n=57). Hospital records and survival data from National Insurance Database were reviewed.
Results : There were 187 heart transplants in 183 patients. The mean age of overall patients was 48.9 ± 14.27 (range, 18~78). There were 57 female patients (30.5%). The mean total ischemic time and aortic cross clamp time were 195.8 ± 60.91 (range, 85~385) and 99 ± 30.89 (range, 48~323), respectively. There was no difference of donor age, graft ischemic times, aortic cross clamp time, and cardiopulmonary bypass time between ECLS and no-ECLS groups. In ECLS group, the mean duration of ECLS before heart transplantation was 12.2 ± 13.13 (range, 0~65; median, 9). Overall 30-day mortality was 5.9% (10.5% in ECLS group and 3.8% in no-ECLS group; p = 0.074). There was no difference in late survival between two groups (Fig. 1, p=0.294).
Conclusion : Although the early mortality of ECLS group seemed to be higher than that of no-ECLS group, the long term survival of ECLS group was reasonably good. In cases of short-term ECLS, the outcome of heart transplantation bridged by ECLS was comparable with that of no-ECLS group.
Methods : We reviewed patients who had heart transplantation between December 2003 and July 2016. We excluded patients under 18 years-old. We defined heart transplantations which was performed while the patients were under ECLS as ECLS group (n=57). Hospital records and survival data from National Insurance Database were reviewed.
Results : There were 187 heart transplants in 183 patients. The mean age of overall patients was 48.9 ± 14.27 (range, 18~78). There were 57 female patients (30.5%). The mean total ischemic time and aortic cross clamp time were 195.8 ± 60.91 (range, 85~385) and 99 ± 30.89 (range, 48~323), respectively. There was no difference of donor age, graft ischemic times, aortic cross clamp time, and cardiopulmonary bypass time between ECLS and no-ECLS groups. In ECLS group, the mean duration of ECLS before heart transplantation was 12.2 ± 13.13 (range, 0~65; median, 9). Overall 30-day mortality was 5.9% (10.5% in ECLS group and 3.8% in no-ECLS group; p = 0.074). There was no difference in late survival between two groups (Fig. 1, p=0.294).
Conclusion : Although the early mortality of ECLS group seemed to be higher than that of no-ECLS group, the long term survival of ECLS group was reasonably good. In cases of short-term ECLS, the outcome of heart transplantation bridged by ECLS was comparable with that of no-ECLS group.
책임저자: Yang Hyun Cho
Department of Thoracic and Cardiovascular Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea
발표자: Yang Hyun Cho, E-mail : mdcho95@gmail.com