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Early Enteral Feeding Compared with Parenteral Nutrition after Esophagectomy in Esophageal Cancer Patients.
Kim Jae Hyun, Kim Dong Won
Department of Thoracic and Cardiovascular Surgery, Dongnam Institute of Radiological and Medical Science, Busan, Republic of Korea

Background : Early enteral feeding after gastrointestinal surgery has become a recommended procedure. However, It is unclear whether early enteral feeding is safe and effective or not in the postoperative course of the patients with esophageal cancer after esophagectomy. The aim of this study was to evaluate the safety and effectiveness of early enteral feeding compared to conventional pareteral nutrition after esophagectomy in esophageal cancer patients.

Methods : We retrospectively analysed the clinical data of 68 esophageal cancer patients underwent esophagectomy in our hospital from August 2010 to April 2015. Patients were divided into two groups. Group E (15 patients) started enteral feeding by the nasogastric tube within postoperative 48 hour and group P (53 patients) started oral feeding at the postoperative 7th day. Clinical factors such as first fecal pass day, total hospital stay, postoperative pulmonary and digestive complication, difference of postoperative serum albumin, difference of postoperative body weight loss, volume of albumin replacement, postoperative CRP level, anastomosis leak and mortality were compared between the groups.

Results : Group E showed significantly fast fecal passage (postoperative 4.4 ± 1.12 day) (p<0.05). Wound infection was significantly lower in group E (p=0.05). However, there was no significant difference in postoperative pulmonary and digestive complications, postoperative nutritional status (body weight, serum albumin) between the two groups. Also, total hospital stay, postoperative CRP level, leak and mortality had no significant difference between the two groups.

Conclusion : These results show that early enteral feeding is safe and promotes early recovery of intestinal movement in the postoperative course of the patients with esophageal cancer after esophagectomy. And early enteral feeding had a positive effect on the postoperative wound management. But early enteral feeding did not show that it was more effective method of the maintenance of postoperative nutritional status and complication compared to conventional pareteral nutrition after esophagectomy.


책임저자: Kim Jae Hyun
Department of Thoracic and Cardiovascular Surgery, Dongnam Institute of Radiological and Medical Science, Busan, Republic of Korea
연락처 : Kim Jae Hyun, Tel: 051-720-5050 , E-mail : cskjh2@dierams.re.kr

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