초록접수 현황
| 15F-067 | 구연 발표 |
Prevalence and Risk Factors of Aortic Root Dilatation Late after Repaired Tetralogy of Fallot
심형태, 김정원, 최은석, 곽재건, 이창하
세종병원 흉부외과
Background : It is known that aortic root dilatation could be developed late after repaired Tetralogy of Fallot (TOF), but its predictors and clinical implications are not well understood. We sought to determine the prevalence and risk factors for aortic root dilatation in adults with repaired TOF.
Methods : An observational retrospective cohort study was conducted in 309 adults (≥18 years) with repaired TOF or pulmonary atresia with ventricular septal defect. The definition of aortic root dilatation was that the absolute diameter of Sinus of Valsalva (SoV) was over 40mm. The measurement of SoV was by Echocardiography in 52 patients, Computed Tomography angiography in 190 patients, and Magnetic Resonance Image in 67 patients.
Results : Median age was 22 years (18 ~ 71 years). Aortic root dilatation was observed in 63 patients (20.4%). Of them, 3 patients underwent Bentall operation because of acute aortic dilatation or aortic root aneurysm. Only 4 patients showed significant aortic regurgitation (AR). On multivariate logistic regression analysis, age (OR=1.08; 95% CI, 1.01 – 1.15; P=0.02), male sex (OR=4.96; 95% CI, 1.84 – 13.41; p=0.002), pulmonary atresia (OR=7.73; 95% CI, 1.48 – 40.25; p=0.015), and previous shunt operation (OR=3.54; 95% CI, 1.12 – 11.21; p=0.032) were signification risk factors for late aortic root diatation.
Conclusion : Aortic root dilatation was not uncommon in adults with repaired TOF and rarely developed to aortic dissection or significant aortic aneurysm. Close follow- up would be necessary to confirm the progression of aortic root dilatation after repaired TOF.
Methods : An observational retrospective cohort study was conducted in 309 adults (≥18 years) with repaired TOF or pulmonary atresia with ventricular septal defect. The definition of aortic root dilatation was that the absolute diameter of Sinus of Valsalva (SoV) was over 40mm. The measurement of SoV was by Echocardiography in 52 patients, Computed Tomography angiography in 190 patients, and Magnetic Resonance Image in 67 patients.
Results : Median age was 22 years (18 ~ 71 years). Aortic root dilatation was observed in 63 patients (20.4%). Of them, 3 patients underwent Bentall operation because of acute aortic dilatation or aortic root aneurysm. Only 4 patients showed significant aortic regurgitation (AR). On multivariate logistic regression analysis, age (OR=1.08; 95% CI, 1.01 – 1.15; P=0.02), male sex (OR=4.96; 95% CI, 1.84 – 13.41; p=0.002), pulmonary atresia (OR=7.73; 95% CI, 1.48 – 40.25; p=0.015), and previous shunt operation (OR=3.54; 95% CI, 1.12 – 11.21; p=0.032) were signification risk factors for late aortic root diatation.
Conclusion : Aortic root dilatation was not uncommon in adults with repaired TOF and rarely developed to aortic dissection or significant aortic aneurysm. Close follow- up would be necessary to confirm the progression of aortic root dilatation after repaired TOF.
책임저자: 이창하
세종병원 흉부외과
연락처 : 이창하, Tel: 010-2549-3356 , E-mail : leechha@sejongh.co.kr
