초록접수 현황
| 14F-099 | 포럼 발표 |
Prognostic Value of Laboratory Findings on Survival during Long-time Extracorporeal Life Support
김희중, 이광형, 이승헌, 정재승, 김태식, 손호성, 선경
고려대학교 의과대학 안암병원 흉부외과학교실
Background : Long duration of extracorporeal life support was inevitable due to improving management technique and severity of patients. However, there was a few study about prognosis evaluation during prolonged ECLS. Aim of our study is investigation of laboratory prognostic factor to predict successful survival after prolonged ECMO.
Methods : This study reviewed the patients who treated with ECMO between 2009 and 2014. We excluded the patients who shorter than 3 day long support and younger than 18 years old. All values were collected such as demographic, clinical, and laboratory data during ECLS. The primary endpoint was survival to discharge.
Results : Forty three patient were enrolled this study.(89 patients were excluded according to study design) Mean age of patient was 54.67 ± 17.4. Male was twenty three(53.5%). Mean ECLS time were 329.36 ± 284.81 hours. Weaning from ECMO were 25/43(58.1%). Overall survival were 13/43(30.2%). In univariate analysis, age, sex, renal replacement therapy were significant prognostic factors.(p<0.05) In laboratory data, maximum value of total bilirubin, International normalized ratio, blood urea nitogen, creatinine, lactate level showed significant prognostic power. (P-value < 0.5)
Conclusion : Our study showed laboratory values of liver and kidney have significant prognostic values. To improve survival rate of ECLS, organ preservation was should be considered.
Methods : This study reviewed the patients who treated with ECMO between 2009 and 2014. We excluded the patients who shorter than 3 day long support and younger than 18 years old. All values were collected such as demographic, clinical, and laboratory data during ECLS. The primary endpoint was survival to discharge.
Results : Forty three patient were enrolled this study.(89 patients were excluded according to study design) Mean age of patient was 54.67 ± 17.4. Male was twenty three(53.5%). Mean ECLS time were 329.36 ± 284.81 hours. Weaning from ECMO were 25/43(58.1%). Overall survival were 13/43(30.2%). In univariate analysis, age, sex, renal replacement therapy were significant prognostic factors.(p<0.05) In laboratory data, maximum value of total bilirubin, International normalized ratio, blood urea nitogen, creatinine, lactate level showed significant prognostic power. (P-value < 0.5)
Conclusion : Our study showed laboratory values of liver and kidney have significant prognostic values. To improve survival rate of ECLS, organ preservation was should be considered.
책임저자: 손호성
고려대학교 의과대학 안암병원 흉부외과학교실
연락처 : 김희중, Tel: 02-920-6638 , E-mail : heejung440@hanmail.net
