초록접수 현황
| 14F-049 | 포스터 발표 |
Clinical Results of Photodynamic Therapy in Tracheobronchial Malignancy
Eunjue Yi1, Ji-Eun Chang1, Chosun Leem1, Sergey Kim1, Sanghoon Jheon1,2
1.Department of Thoracic and Cardiovascular Surgery, Seoul National University Bundang Hospital, Seongnam-Si, Gyeonggi-do, Republic of Korea
2.Department of Thoracic and Cardiovascular Surgery, Seoul National University College of Medicine, Seoul, Republic of Korea
Background : Photodynamic therapy (PDT) initially adopted as emergency treatment for resolving airway obstructions by tumor. But it gradually had expanded its roles in lung cancer treatment for curative intention. We reviewed 25 cases of photodynamic therapy for tracheobronchial malignancy in Seoul National University Bundang Hospital, therefore aimed to evaluate the feasibility of PDT in tracheobronchial malignancy.
Methods : Medical records of patients of tracheobronchial cancers who received photodynamic therapies were reviewed retrospectively. Outcomes of the treatment results were evaluated. And survival analysis was performed via Kaplan-Meir methods.
Results : We performed 25 cases of photodynamic therapy for tracheobronchial cancer patients between 2003 and 2013. A total of 21 patients were involved. (1 female and 19 males) Average ages at the time of treatment were 68.1. In those 25 cases, 8 cases (32.0%) had achieved complete remission, 16 cases (60.0%) remained partial remission. There were 2 (8.0%) cases of no response. Seven patients died during the follow up periods, but none of these were related with complications. Only two of minor complications were observed during the follow up periods. One was granulation at the site of PDT, and the other was hemoptysis. Average overall survival periods for therapeutic group were 50.1(±34.14) months and those of palliative group were 29.3(±28.20) months.
Conclusion : Photodynamic therapy was safe and feasible for palliative therapy in tracheobronchial cancer with acceptable complication rates. Also, it could be a therapeutic option for early stage lung cancer of tracheobronchial trees when the patient has inoperable condition.
Methods : Medical records of patients of tracheobronchial cancers who received photodynamic therapies were reviewed retrospectively. Outcomes of the treatment results were evaluated. And survival analysis was performed via Kaplan-Meir methods.
Results : We performed 25 cases of photodynamic therapy for tracheobronchial cancer patients between 2003 and 2013. A total of 21 patients were involved. (1 female and 19 males) Average ages at the time of treatment were 68.1. In those 25 cases, 8 cases (32.0%) had achieved complete remission, 16 cases (60.0%) remained partial remission. There were 2 (8.0%) cases of no response. Seven patients died during the follow up periods, but none of these were related with complications. Only two of minor complications were observed during the follow up periods. One was granulation at the site of PDT, and the other was hemoptysis. Average overall survival periods for therapeutic group were 50.1(±34.14) months and those of palliative group were 29.3(±28.20) months.
Conclusion : Photodynamic therapy was safe and feasible for palliative therapy in tracheobronchial cancer with acceptable complication rates. Also, it could be a therapeutic option for early stage lung cancer of tracheobronchial trees when the patient has inoperable condition.
책임저자: 전상훈
Department of Thoracic and Cardiovascular Surgery, Seoul National University Bundang Hospital
연락처 : 이은주, Tel: 031-787-7146 , E-mail : viking99@hanmail.net
