초록접수 현황
| 14F-253 | 구연 발표 |
Aortic Valve Replacement in Patients Aged 50 to 70 Years : Evaluation of Mechanical Versus Biologic Valves
Seungjun Song, Seung Hyun Lee, Byung-Chul Chang, Kyung-Jong Yoo, Sak Lee
Division of Cardiovascular Surgery, Severance Cardiovascular Hospital, Yonsei University College of Medicine
Background : Because of the improved durability of bioprostheses(BP), the use of BP has markedly increased in the past decade for patients younger than 65 years. The aim of this study was to determine long-term results between BP and mechanical(MP) aortic valves in patients aged 50 to 70 years.
Methods : Between January 1990 and December 2013, overall survival, thromboembolism, hemorrhagic events, re-operation were analyzed in all patients aged 50 to 70 years of age. Groups were matched one-to-one according to age, sex, need for coronary artery bypass grafting, and valve size. The mean follow-up was 75.72 ± 64.36 months(range, 1.7-299.3), 80.2 months for patients who received MP and 71.2 months for patients who received BP (p=0.215). The mean age at operation was 64.88±3.52 years.
Results : 316 patients were matched. At late follow-up 26 patients(16.5%) died in the MP group and 35 patients died in the BP group (p=0.2). There were no significant differences in the hemorrhagic events rate and thromboembolism rate between two groups. The 10-year survivals were 81.8% for MP and 73.3% for BP (p=0.063)
Conclusion : In this study, patients undergoing aortic valve replacement(AVR) either with MP or BP valves had a similar rate of occurrence of thromboembolism and hemorrhagic events. The patients with MP tend to survive more than the patients with BP. AVR with MP seems to be an advantageous solution in patients 50 to 70 years of age, but further investigations are needed to clarify the situation.
Methods : Between January 1990 and December 2013, overall survival, thromboembolism, hemorrhagic events, re-operation were analyzed in all patients aged 50 to 70 years of age. Groups were matched one-to-one according to age, sex, need for coronary artery bypass grafting, and valve size. The mean follow-up was 75.72 ± 64.36 months(range, 1.7-299.3), 80.2 months for patients who received MP and 71.2 months for patients who received BP (p=0.215). The mean age at operation was 64.88±3.52 years.
Results : 316 patients were matched. At late follow-up 26 patients(16.5%) died in the MP group and 35 patients died in the BP group (p=0.2). There were no significant differences in the hemorrhagic events rate and thromboembolism rate between two groups. The 10-year survivals were 81.8% for MP and 73.3% for BP (p=0.063)
Conclusion : In this study, patients undergoing aortic valve replacement(AVR) either with MP or BP valves had a similar rate of occurrence of thromboembolism and hemorrhagic events. The patients with MP tend to survive more than the patients with BP. AVR with MP seems to be an advantageous solution in patients 50 to 70 years of age, but further investigations are needed to clarify the situation.
책임저자: 이삭
Division of Cardiovascular Surgery, Severance Cardiovascular Hospital, Yonsei University College of Medicine
연락처 : 송승준, Tel: 02-2228-8495 , E-mail : songseungjun@gmail.com
