초록접수 현황
| 14F-196 | 구연 발표 |
The Renal Effect of Prophylactic Aminophylline Therapy after Cardiac Surgery in Infants
정인석, 강승구, 김도완, 김순진, 오봉석, 안병희, 김상형
전남대학교병원 흉부외과
Background : Acute kidney injury (AKI) after pediatric cardiac surgery remains important complication. Aminophylline, an well established bronchodilator, is also considered to be an effective diuretic and anti-inflammatory agent. We evaluated the effect of prophylactic aminophylline treatment after cardiac surgery in infants.
Methods : From January 2009 to June 2014, 84 infants undergoing operation for isolated ventricular septal defect were classified to the prophylactic aminophylline therapy group (N=48) and the control group (N=36). This is a retrospective analysis of urine output, fluid overload and duration of oliguira/anuria between 2 groups in postoperative period.
Results : There was no statistical significance of pre- and intra-operative factors in 2 groups. Average daily urine output increased by 0.36 mL/kg/hr (p = 0.03), and daily input / output (I/O) balance decreased on average by 0.65 % per day in the postoperative 2nd and 3rd day (p = 0.01). There were no complications related to aminophylline administration.
Conclusion : We suggest that administration of aminophylline successfully promoted increased urine output in immediate postoperative period. The prospective studies are necessary to confirm the safety and effectiveness of prophylactic application.
Methods : From January 2009 to June 2014, 84 infants undergoing operation for isolated ventricular septal defect were classified to the prophylactic aminophylline therapy group (N=48) and the control group (N=36). This is a retrospective analysis of urine output, fluid overload and duration of oliguira/anuria between 2 groups in postoperative period.
Results : There was no statistical significance of pre- and intra-operative factors in 2 groups. Average daily urine output increased by 0.36 mL/kg/hr (p = 0.03), and daily input / output (I/O) balance decreased on average by 0.65 % per day in the postoperative 2nd and 3rd day (p = 0.01). There were no complications related to aminophylline administration.
Conclusion : We suggest that administration of aminophylline successfully promoted increased urine output in immediate postoperative period. The prospective studies are necessary to confirm the safety and effectiveness of prophylactic application.
책임저자: 정인석
전남대학교병원 흉부외과
연락처 : 정인석, Tel: 062-220-6546 , E-mail : isjeong1201@gmail.com
