Left Ventricular Remodeling after Mitral Valve Replacement in Patient with Isolated Mitral Regurgitation
Jong Hyun Baek, Myung Soo Kim, Young Uk Lee, Tae Eun Jung, Dong Hyup Lee, Jang Hoon Lee, Jung Cheol Lee
Department of Thoracic and Cardiovascular Surgery, College of Medicine, Yeungnam University
Background : The objective of this study was to evaluate changes in the postoperative left ventricular ejection fraction (LVEF) and dimensions following mitral valve replacement (MVR) in patients with isolated mitral regurgitation (MR).
Methods : There were 19 patients (9 males, 9 females, mean age 56.5 ± 11.0 years, and mean follow up 35.5 ± 24.7 months) with isolated MR between 2005 and 2011. Echocardiographic data were collected retrospectively at preoperative and last follow up. There was no reoperation case during follow up period. We excluded acute MR and bacterial endocarditis. The patients were divided into decreased LVEF group (group A: less than 55%, 11 cases) and normal LVEF group (group B: more than 55%, 8 cases)
Results : Preoperative LVEF of group A was 46.9 ± 6.7% and group B was 64.4 ± 5.2%. Left ventricular ejection fraction of preoperative and last follow up period were no significant changes (group A; 46.9 ± 6.7% vs 54.8 ± 14.1%, p=0.065 : group B; 62.9 ± 3.2% vs 59.3 ± 5.6% , p=0.064) in both groups. Left ventricular end diastolic dimension and end systolic dimension significantly decreased after MVR in group A (60.5 ± 5.0% vs 54.0 ± 9.3%, p=0.005: 42.7 ± 7.7% vs 38.1 ± 12.0%, p=0.045). Left atrial volume index was significantly decreased in group A (81.3 ± 43.0 vs 52.7 ± 27.5, p=0.0011). Preoperative left ventricular end systolic dimension was different between two groups (group A; 42.7 ± 7.7% vs 34.8 ± 4.6, p=0.021). However, postoperative dimension were no significant difference (group A; 38.1 ± 12.0% vs 32.4 ± 4.6, p=0.174). Remain parameters, septum thickness, left ventricular posterior wall thickness, left ventricular muscle mass index, and left atrial volume index were no significant difference between two groups at postoperative period.
Conclusion : This study showed that the results of mitral valve replacement in patients with left ventricular dysfunction comparable with normal left ventricular function in isolated mitral regurgitation.
책임저자: Dong Hyup Lee
Department of Thoracic and Cardiovascular Surgery, College of Medicine, Yeungnam University
연락처 : Jong Hyun Baek, Tel: 053-620-3880 , E-mail : yumc2000@hanmail.net